Cerebelum 7b (Left)

Overview

The left Cerebelum 7b (Left) region in the AAL2 atlas corresponds to part of lobule VIIb of the posterior cerebellar hemisphere on the left side. This lobule is implicated in higher-order cognitive and associative functions rather than primary motor control, participating in cortico-cerebellar loops with prefrontal and parietal association cortices. Functional imaging studies link cerebellar lobule VIIb to processes such as working memory, attention, and aspects of language and executive control, reflecting the cerebellum’s broader role in modulating cognitive and affective operations in addition to fine-tuning movement. There is no direct Wikipedia article for “Cerebelum 7b (Left)”; a related structure is the posterior cerebellar hemisphere: Cerebellum.

The left cerebellar lobule VIIb (AAL2 “Cerebelum_7b_L”) has been implicated in several imaging–genetics and GWAS-based endophenotype studies, although direct region-specific genetic evidence remains relatively sparse compared with cortical areas. Large-scale brain structure GWAS (e.g., ENIGMA and UK Biobank–based analyses) have identified common variants in genes involved in neurodevelopment, synaptic function, and neuronal signaling—such as variants near or within genes related to axon guidance, cell adhesion, and calcium channel function—that associate with volumetric measures of posterior cerebellar lobules, including VIIb. Polygenic risk analyses have linked cerebellar volume and morphology to schizophrenia, major depressive disorder, bipolar disorder, autism spectrum disorder, and attention-deficit/hyperactivity disorder, with some of these effects observable in posterior cerebellar regions encompassing VIIb, suggesting that shared genetic architectures for these psychiatric conditions partly manifest through cerebellar structural variation. In addition, GWAS of general cognitive ability and educational attainment have reported that genetic scores for these traits correlate with gray matter volume and functional connectivity in posterior cerebellar territories, including regions overlapping VIIb, consistent with the role of this lobule in higher-order cognitive and affective processing; however, specific single-gene or variant associations uniquely and consistently assigned to left VIIb alone have not yet been robustly established.

Overview generated by GPT-4o (2026).

Region ID: 9051
Hemisphere: left
Atlas: AAL2

Cerebelum 7b (Left) – Black Background (Full Brain)

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Cerebelum 7b (Left) – White Background (Full Brain)

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Cerebelum 7b (Left) – Black Background (Hemisphere)

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Cerebelum 7b (Left) – White Background (Hemisphere)

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Triplanar View – T1 Background

Triplanar View – Ghost Brain