MASI Lab · Vanderbilt University
Brain atlases are essential for interpreting neuroimaging results, yet no publicly accessible, precomputed resource for comparing regions across atlases in 3D has existed — until now. SPINS provides interactive visualizations across cortical, subcortical, white matter, and functional parcellations.
Available atlases
Manually labeled human neuroanatomical parcellation delineating hundreds of cortical and subcortical structures on high-resolution MRI.
Automated Anatomical Labeling atlas: a macroanatomical parcellation dividing the cortex and some subcortical structures by sulcal landmarks.
Automated Anatomical Labeling 2: a parcellation in standard MNI space subdividing the cerebrum and cerebellum into anatomical regions.
Large-scale cortical parcellation dividing the cerebral cortex into 17 intrinsic functional networks from resting-state fMRI connectivity.
White-matter tract parcellation from the Pandora dataset, aggregating multi-cohort diffusion MRI processed with the TractSeg framework.
Probabilistic, population-based parcellation of major white matter tracts and selected gray matter regions from diffusion and structural MRI.
Johns Hopkins white-matter labels atlas at 1mm resolution, defining major tracts and pathways.
Probabilistic atlas of major white-matter fiber tracts derived from diffusion tractography.
Probabilistic atlas of major white-matter fiber tracts at 1mm resolution.
Probabilistic parcellation of the human thalamus from diffusion-weighted MRI connectivity profiles, classifying thalamic voxels by cortical connectivity.
Probabilistic parcellation of the human thalamus into major nuclei from connectivity profiles, at 1mm resolution.
Coarse structural parcellation of the brain into major lobes and subcortical structures.
Coarse structural parcellation of the brain into major lobes and subcortical structures, at 1mm resolution.
Probabilistic atlas of subcortical gray-matter structures in standard space.
Probabilistic atlas of subcortical gray-matter structures at 1mm resolution.
Probabilistic parcellation of the cerebral cortex into anatomically defined regions.
Probabilistic parcellation of the cerebral cortex at 1mm resolution.
Cytoarchitectonic atlas mapping cortical areas and subcortical nuclei across the brain.
Cytoarchitectonic atlas mapping cortical areas and subcortical nuclei, at 1mm resolution.
Hierarchical whole-brain labeling based on the Talairach coordinate system.
Hierarchical whole-brain labeling based on the Talairach coordinate system, at 1mm resolution.
Motivation
Brain atlases are essential for interpretation of results and communication, yet atlas choice can substantially affect research conclusions. Despite this, no publicly accessible, precomputed resource to compare regions across atlases in 3D has existed.
SPINS makes this comparison immediately accessible, with no software installation required. Each region page includes an AI-generated anatomical overview, rotating glass brain videos, and triplanar slice images.
Pipeline