The right Cerebelum 7b (Right) in the AAL2 atlas corresponds to a lateral region of the posterior cerebellar hemisphere, generally overlapping parts of lobule VII (particularly Crus II and adjacent territories), which is implicated more in higher-order cognitive and associative functions than in primary motor control. This area participates in cerebro-cerebellar loops with prefrontal and parietal cortical regions, contributing to processes such as working memory, language, attention, and executive control, as well as fine-tuning complex, learned motor sequences. Functionally, activity in this region is often observed in tasks involving cognitive flexibility, planning, and the coordination of mental operations rather than simple movement execution. There is no direct Wikipedia entry for “Cerebelum 7b”; a related structure is the Cerebellum.
Genetic associations specifically targeting the AAL2 right Cerebellum 7b region are limited, as most GWAS and imaging genetics studies analyze cerebellar volumes or lobular subregions rather than fine-grained AAL parcels; however, several findings implicate cerebellar territory overlapping Crus II/7b in cognitive and psychiatric traits. Large neuroimaging GWAS (e.g., ENIGMA, UK Biobank) have identified variants in loci such as KIAA0586, PAPPA2, and others associated with total cerebellar volume and specific posterior cerebellar regions, which include areas near 7b, and these cerebellar volume–associated variants are in turn genetically correlated with intelligence, educational attainment, and neurodevelopmental traits. Polygenic risk scores for schizophrenia, bipolar disorder, autism spectrum disorder, and major depressive disorder show associations with altered structure and connectivity in posterior cerebellar regions, including right lateral/posterior cerebellum, although not always isolating 7b. Functional imaging and imaging–genetics work suggests that genetically driven variation in default-mode and frontoparietal networks—linked via loci in genes such as CACNA1C, GRM3, and others—extends to cerebellar nodes in Crus II/7b that support executive function, language, and working memory, thereby connecting risk alleles for psychiatric disorders and cognitive traits to this territory through network-level rather than region-specific GWAS signals. Overall, current evidence ties the broader posterior lateral cerebellum containing the AAL2 right Cerebellum 7b region to polygenic influences on cognition and psychiatric vulnerability, but direct region-specific genetic associations remain sparse and are generally inferred from volumetric or connectivity measures rather than discrete GWAS hits for this exact parcel.
Overview generated by GPT-4o (2026).
Region ID: 9052
Hemisphere: right
Atlas: AAL2

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Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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