Cerebelum 8 (Left)

Overview

The left Cerebelum 8 region in the AAL2 atlas corresponds to a subdivision of lobule VIII of the left cerebellar hemisphere, part of the posterior lobe of the cerebellum. This lobule is primarily involved in sensorimotor processing, particularly in the fine-tuning of limb movements, balance, and coordination, and is functionally connected with motor and premotor cortical areas as well as somatosensory pathways. It contributes to the timing and precision of movements and may also participate in aspects of motor learning and adaptation. There is no direct Wikipedia article for “Cerebelum 8”; a closely related structure is the posterior lobe of the cerebellum: Posterior lobe of cerebellum.

The left Cerebellum 8 region (AAL2) has relatively limited region-specific genetic characterization, but several lines of evidence from imaging genetics and GWAS implicate it indirectly via broader cerebellar and lobule VIII findings. Large-scale brain-structure GWAS (e.g., ENIGMA, UK Biobank) have identified variants in genes linked to neurodevelopment, synaptic function, and axon guidance—such as MAPT, RELN, and genes in calcium-channel (CACNA) and glutamatergic pathways—associated with total cerebellar volume and, in some analyses, lobule VIII–adjacent measures, although parcellations rarely isolate AAL2 Cerebellum 8 (Left) specifically. Functional imaging and imaging–genetic studies connect lobule VIII with sensorimotor control, timing, and aspects of cognitive and affective processing, and genes influencing these systems overlap with risk loci for movement disorders, autism spectrum disorder, schizophrenia, and mood disorders, which often show altered cerebellar structure or activation, including in posterior–inferior lobules. Polygenic risk for psychiatric and neurodevelopmental conditions has been associated with distributed cerebellar volume changes, and some GWAS of traits such as motor coordination, balance, and cognitive performance report cerebellar structural correlates that encompass lobule VIII regions, but to date there are no robust, replicated single-gene or SNP associations uniquely and specifically assigned to the left Cerebellum 8 AAL2 parcel.

Overview generated by GPT-4o (2026).

Region ID: 9061
Hemisphere: left
Atlas: AAL2

Cerebelum 8 (Left) – Black Background (Full Brain)

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Cerebelum 8 (Left) – White Background (Full Brain)

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Cerebelum 8 (Left) – Black Background (Hemisphere)

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Cerebelum 8 (Left) – White Background (Hemisphere)

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Triplanar View – T1 Background

Triplanar View – Ghost Brain