Cerebelum 8 (Right)

Overview

Cerebelum_8_R (Right Cerebellum Lobule VIII) in the AAL2 atlas corresponds primarily to lobule VIII of the cerebellar hemisphere on the right side, a region located in the posterior lobe of the cerebellum and involved in sensorimotor integration, fine-tuning of limb movements, balance, and coordination of complex motor tasks. Functionally, this lobule participates in error correction during movement, contributes to timing and precision of voluntary motor output, and integrates proprioceptive and vestibular information to maintain postural control. Neuroimaging studies indicate that lobule VIII is activated during hand and finger movements, gait-related tasks, and some aspects of oculomotor control, reflecting its role in refining ongoing motor commands rather than initiating them. There is no direct link for “Cerebelum_8_R”; a related structure with a dedicated article is Cerebellum.

Genetic associations specifically implicating the AAL2 “Cerebelum_8_R” region are limited, but several large-scale imaging genetics studies and GWAS of brain structure have reported links between common variants and volumetric or functional variation in lobule VIII of the cerebellum, often in the context of broader cerebellar measures. Variants in genes involved in synaptic development, neurodevelopment, and neuronal signaling (e.g., KIAA0586, DLG2, and others identified in ENIGMA and UK Biobank-based brain MRI GWAS) have been associated with cerebellar gray matter volume and cortical thickness, with some loci showing regional effects in posterior cerebellar lobules including VIII. Cerebellar lobule VIII has been implicated functionally in sensorimotor integration and aspects of cognitive and affective processing, and polygenic risk scores for neurodevelopmental and psychiatric conditions such as autism spectrum disorder, schizophrenia, ADHD, and major depression have been associated with structural or functional alterations in cerebellar territories encompassing lobule VIII. In addition, GWAS of motor coordination, balance, intelligence, and educational attainment have shown overlap between trait-associated loci and genes whose expression or regulatory elements are enriched in cerebellar tissue, suggesting that genetically driven variation in cerebellar microstructure, including right lobule VIII, contributes to individual differences in motor and cognitive phenotypes, although precise, lobule-specific genetic mappings remain under active investigation rather than being firmly established.

Overview generated by GPT-4o (2026).

Region ID: 9062
Hemisphere: right
Atlas: AAL2

Cerebelum 8 (Right) – Black Background (Full Brain)

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Cerebelum 8 (Right) – White Background (Full Brain)

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Cerebelum 8 (Right) – Black Background (Hemisphere)

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Cerebelum 8 (Right) – White Background (Hemisphere)

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Triplanar View – T1 Background

Triplanar View – Ghost Brain