The bilateral Tapetum R, as defined in the JHU ICBM 2mm white matter atlas, is a right-hemispheric portion of the tapetum, a thin sheet of callosal fibers that runs along the lateral and inferior aspect of the lateral ventricle and forms part of the splenial extension of the corpus callosum. These fibers interconnect temporal lobe structures across hemispheres, contributing to interhemispheric transfer of auditory, language-related, and multimodal associative information, particularly between medial and lateral temporal cortices. Anatomically, the tapetum lies adjacent to the temporal horn of the lateral ventricle and is continuous with other callosal fiber systems, reflecting its role in coordinated bilateral temporal lobe function and integration of higher-order sensory and cognitive processes. There is no dedicated Wikipedia article for the tapetum (white matter tract); a related structure is the Corpus callosum.
The bilateral tapetum, a small callosal fiber tract carrying interhemispheric visual and auditory information, has been implicated indirectly in genetic studies that focus on white-matter microstructure and callosal pathways rather than on this tract alone; diffusion tensor imaging (DTI) GWASs using the JHU ICBM 2 mm atlas have reported heritable variance in fractional anisotropy and other diffusion metrics in callosal and temporal association fibers that include or border the tapetum, with polygenic influences involving genes related to axon guidance, myelination, and neurodevelopment (for example, loci near genes such as NRG1, CNTN4, and PLP1 in broader callosal or temporal white matter). While no large GWAS has identified tapetum-specific genome-wide significant loci by name, genetic factors that affect overall corpus callosum integrity, temporal lobe connectivity, and global white-matter organization—often studied in the context of schizophrenia, bipolar disorder, autism spectrum disorder, and major depression—are likely to influence this region, as suggested by patient–control imaging-genetics work showing altered callosal and temporal white matter in carriers of risk variants in neurodevelopmental and synaptic genes.
Overview generated by GPT-4o (2026).
Region ID: 47
Hemisphere: bilateral
Atlas: JHU ICBM labels 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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