The bilateral GM Superior parietal lobule 7PC R, as defined in the Juelich maxprob thr25 1mm Atlas, corresponds to a cytoarchitectonically characterized subregion of Brodmann area 7 located in the posterior part of the superior parietal lobule of the right hemisphere. This region is associated with higher-order somatosensory integration, spatial attention, and visuomotor coordination, contributing to the representation and manipulation of body-centered and object-centered spatial information. Neuronal populations within 7PC participate in the integration of proprioceptive, tactile, and visual inputs to guide goal-directed actions, including reaching and grasping, and are involved in the transformation of sensory information into motor plans. Functionally, this area forms part of the dorsal attention and sensorimotor networks, with strong connectivity to premotor and parietal regions that support spatial working memory and the online control of movements. There is no direct Wikipedia article for “Superior parietal lobule 7PC”; a related structure is the Superior parietal lobule.
The bilateral GM Superior parietal lobule (SPL), including the 7PC subregion in right hemisphere as defined in the Juelich maxprob thr25 1mm atlas, has been implicated in genetic studies primarily through imaging‑genetics and GWAS of brain structure and cognitive traits rather than direct, region‑specific gene associations. Large GWAS of cortical morphology (e.g., ENIGMA, UK Biobank) have identified multiple loci influencing parietal cortical thickness and surface area—such as variants near genes involved in neurodevelopment, synaptic function, and cytoskeletal organization (including but not limited to CENPO, DACT1, and other loci on chromosomes 6, 8, and 17)—with some effects overlapping SPL territory, though these findings typically aggregate across broader parietal regions and do not isolate 7PC specifically. SPL is consistently implicated in heritable individual differences in visuospatial attention, working memory, and numerical cognition, and polygenic scores for cognitive performance and educational attainment show associations with parietal cortical measures that include this region. In psychiatric and neurological genetics, parietal lobule structure and function, encompassing SPL, has been linked to risk variants for schizophrenia, ADHD, autism spectrum disorder, and Alzheimer’s disease through intermediate phenotypes such as altered parietal connectivity or cortical thickness, but these relationships are usually network‑level and not specific to 7PC. Overall, genetic influences on SPL 7PC R are supported indirectly via broad parietal cortex GWAS and imaging‑genetic studies of cognition and neuropsychiatric disorders, with no current evidence for a unique, well‑characterized genetic signature confined to this exact atlas-defined subregion.
Overview generated by GPT-4o (2026).
Region ID: 78
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 1mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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