The bilateral GM Anterior intra-parietal sulcus hIP1 R region from the Juelich maxprob thr25 2mm atlas corresponds to a cytoarchitectonically defined subdivision of the human intraparietal sulcus implicated in visuomotor integration, object-directed grasping, and higher-order sensorimotor transformations. Located in the posterior parietal cortex, this area contributes to processing of three-dimensional object features (such as size, orientation, and shape) and to coordination of hand and eye movements necessary for precision grip and manipulation. Functionally, hIP1 participates in dorsal stream networks supporting spatial attention, action planning, and the transformation of visual information into motor commands. There is no direct link for this specific subregion; a related structure is the Intraparietal sulcus.
The bilateral GM Anterior intra-parietal sulcus hIP1 R, as defined in the Juelich maxprob thr25 2mm atlas, corresponds to anterior portions of the intraparietal sulcus involved in visuomotor integration, attention, and higher-order sensorimotor processing; while direct locus-specific genetic associations for the hIP1 R label are limited, GWAS and imaging-genetics studies of parietal and intraparietal cortex more broadly have implicated variants in genes related to synaptic development, neuronal migration, and cortical patterning (e.g., BDNF, CNTNAP2, FOXP2, and several glutamatergic signaling genes) in shaping structural and functional properties of this region. Polygenic influences on cortical thickness and surface area of parietal regions have been repeatedly demonstrated, and intraparietal sulcus measures are commonly included in large-scale imaging GWAS (such as UK Biobank-based studies), revealing distributed genetic architectures rather than single strong locus effects. Functionally, intraparietal areas including hIP1 have been linked through genetic and imaging-genetics work to neurodevelopmental and psychiatric conditions such as autism spectrum disorder, attention-deficit/hyperactivity disorder, schizophrenia, and dyslexia, where risk variants influence parietal activation during attention, working memory, numerical cognition, and eye–hand coordination tasks. In addition, common variants associated with cognitive performance, educational attainment, and general intelligence show downstream effects on parietal network structure and function that encompass intraparietal regions, and rare mutations affecting parietal cortical development can contribute to visuospatial deficits and apraxia, collectively indicating that hIP1 lies within a genetically sensitive parietal hub for cognitive and sensorimotor traits.
Overview generated by GPT-4o (2026).
Region ID: 2
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 2mm
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Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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