The bilateral GM Superior parietal lobule 7A R, as defined in the Juelich maxprob thr25 2mm Atlas, corresponds to a cytoarchitectonic subdivision of Brodmann area 7 located in the superior parietal lobule of the right hemisphere, with homologous tissue in the left hemisphere often considered in bilateral analyses. This region is associated with higher-order somatosensory integration, visuospatial processing, and the coordination of attention and sensorimotor transformations, contributing to body-centered spatial representation and goal-directed actions such as reaching and grasping. Neurons in 7A integrate visual and proprioceptive inputs to support accurate spatial localization and movement guidance, and the area is interconnected with dorsal visual stream regions, premotor cortex, and other parietal association areas. There is no direct Wikipedia article for “Area 7A”; a closely related structure is the Superior parietal lobule.
The bilateral GM Superior parietal lobule 7A R (Juelich maxprob thr25 2mm Atlas) corresponds to a multimodal association area involved in visuospatial attention, sensorimotor integration, and higher-order cognition, and genetic associations identified for superior parietal lobule and adjacent parietal cortex often implicate neurodevelopmental and synaptic pathways rather than region-specific “7A R” variants. Large-scale neuroimaging GWAS (e.g., ENIGMA, UK Biobank) have linked common variants in genes such as HMGA2, IGF1, CDK5RAP2, and other loci involved in brain growth and cortical morphology to parietal cortical thickness and surface area, which encompass superior parietal regions including 7A. Parietal lobule structure and function, including activity patterns overlapping 7A, have been associated with genetic risk for attention-deficit/hyperactivity disorder and autism spectrum disorder through polygenic risk scores and gene sets influencing synaptic plasticity, neuronal migration, and axon guidance, although these findings generally refer to broader parietal networks rather than a single cytoarchitectonic subregion. Schizophrenia and major depressive disorder GWAS, as well as imaging-genetics studies, have implicated parietal cortex (including superior parietal areas) in disease-related alterations of connectivity and cortical thickness that correlate with polygenic risk, with enrichment in genes involved in glutamatergic signaling and calcium-channel function. Additionally, parietal regions overlapping 7A are frequently implicated in GWAS of cognitive traits such as general intelligence, educational attainment, and working memory, where associated variants often map to genes regulating neurodevelopment, synaptic formation, and myelination, suggesting that genetic influences on these traits partly act through structural and functional variation in superior parietal cortex rather than discrete, uniquely identified genetic associations for the specific 7A R parcel.
Overview generated by GPT-4o (2026).
Region ID: 74
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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