The bilateral GM Superior parietal lobule 7M R (Juelich maxprob thr25 2mm Atlas) corresponds to the medial subdivision of Brodmann area 7 within the superior parietal lobule, located on the medial surface of the posterior parietal cortex near the precuneus. This region is implicated in higher-order visuospatial processing, sensorimotor integration, and aspects of spatial attention and body-centered representation, contributing to the transformation of sensory input into coordinated actions and to the maintenance of spatial working memory. Functionally, area 7M participates in integrating visual, somatosensory, and proprioceptive information, supporting tasks such as reaching, grasping, and navigation in space, and is involved in the broader network for attention and self-location in the environment. There is no direct link for “Superior parietal lobule 7M”; a related structure is the Superior parietal lobule.
The bilateral GM Superior parietal lobule 7M (right hemisphere) in the Juelich maxprob atlas corresponds to a higher-order parietal region implicated in visuospatial attention, sensorimotor integration, and aspects of working memory, and genetic associations to this area are largely inferred from GWAS and imaging-genetics studies of cortical structure and function rather than region-specific candidate gene work. Large-scale neuroimaging GWAS (e.g., ENIGMA, UK Biobank) have identified common variants in genes involved in neurodevelopment, synaptic function, and cell adhesion (such as variants near HMGA2, KIAA0586, and multiple loci in Wnt and axon guidance pathways) that are associated with parietal cortical surface area, thickness, or overall parietal lobe volume, which likely encompass the 7M subregion but do not isolate it with anatomical precision. Functional connectivity and task-based imaging genetics have linked polygenic risk scores for schizophrenia, autism spectrum disorder, and attention-deficit/hyperactivity disorder to altered activation and connectivity in superior parietal territories, including right-lateralized regions overlapping 7M, consistent with this area’s role in attentional control and visuospatial processing. GWAS of cognitive traits such as general intelligence, working memory performance, and mathematical ability have shown that polygenic influences on these traits partly manifest through structural and functional variation in superior parietal cortices, and parietal regions including 7M are recurrently implicated in mediation analyses linking genetic risk to behavior via brain measures. However, no robust, widely replicated GWAS has yet singled out the right 7M parcel as having unique or dominant genetic associations distinct from adjacent parietal areas, and current evidence supports a distributed polygenic architecture in which many variants with small effects jointly influence morphology and activity across the broader superior parietal network.
Overview generated by GPT-4o (2026).
Region ID: 76
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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