The bilateral GM Superior parietal lobule 7PC R, as defined in the Juelich maxprob thr25 2mm Atlas, corresponds to a cytoarchitectonic subdivision of Brodmann area 7 within the superior parietal lobule, located dorsally in the posterior parietal cortex. This region is implicated in higher-order sensorimotor integration, spatial attention, and visuomotor coordination, contributing to the transformation of sensory input into action-relevant representations and supporting functions such as hand-eye coordination and spatial working memory. Neurally, it participates in distributed parietal–frontal networks involved in body-centered reference frames, movement planning, and the integration of visual, somatosensory, and proprioceptive information. There is no direct Wikipedia article for 7PC; a closely related and encompassing structure is the Superior parietal lobule.
The bilateral GM Superior parietal lobule 7PC R region (as defined in the Juelich maxprob thr25 2 mm atlas) lies within the superior parietal lobule, a hub for visuospatial integration, attention, and sensorimotor coordination, and genetic associations involving this area are typically identified via imaging genetics and GWAS of cortical thickness, surface area, and functional activation rather than region-specific candidate genes. Large-scale consortia such as ENIGMA and UK Biobank have reported that variants near genes involved in neurodevelopment, synaptic function, and axon guidance (for example, MAPT on 17q21.31, microtubule- and cytoskeleton-related genes, and broader neurodevelopmental pathways) influence parietal lobe morphometry, including superior parietal regions overlapping or adjacent to 7PC, with polygenic effects rather than single high-impact loci. GWAS of cognitive traits have repeatedly implicated parietal association cortex, linking common variants that affect superior parietal thickness or activation to general cognitive ability, working memory, and educational attainment, while imaging-genetic studies in Alzheimer’s disease, schizophrenia, and autism spectrum disorders have shown that risk alleles (e.g., APOE ε4 and multiple schizophrenia polygenic risk variants) are associated with altered superior parietal structure or connectivity, including right-hemisphere posterior superior parietal subregions. Additional studies in attention-deficit/hyperactivity disorder, developmental dyslexia, and visuospatial neglect have demonstrated that polygenic risk scores and specific neurodevelopmental loci modulate structure and function in dorsal parietal networks that include 7PC, although current spatial resolution and parcellation differences mean that most reported associations are for the superior parietal lobule broadly rather than the 7PC R parcel specifically.
Overview generated by GPT-4o (2026).
Region ID: 78
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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