The bilateral WM Acoustic radiation L, as defined in the Juelich maxprob thr25 2mm atlas, refers to left-hemispheric white matter fibers of the acoustic (auditory) radiation, which convey auditory information from the medial geniculate nucleus of the thalamus to primary and secondary auditory cortices in the temporal lobe. These fibers course through the sublenticular part of the internal capsule and are integral to the transmission and processing of sound, including basic auditory perception and more complex functions such as speech and music processing. As a white matter tract, the acoustic radiation forms part of the broader auditory pathway and interacts with cortical and subcortical structures involved in sound localization, frequency discrimination, and auditory scene analysis. There is no direct Wikipedia article for the bilateral WM Acoustic radiation L; a related structure is the Auditory radiation.
The bilateral WM Acoustic Radiation L region in the Juelich maxprob thr25 2mm atlas corresponds to the left acoustic (auditory) radiation, a key white matter tract conveying auditory information between the medial geniculate nucleus of the thalamus and primary auditory cortex. Genetic associations for this specific tract at the fine-grained Juelich atlas level have not been systematically cataloged, but GWAS of diffusion MRI–derived white matter measures and auditory cortex structure implicate polygenic influences on microstructural integrity (e.g., fractional anisotropy and mean diffusivity) and cortical thickness in adjacent temporal lobe regions. Variants in genes involved in axon guidance, myelination, and synaptic function (such as CNTNAP2, FOXP2, and neurodevelopmental pathway genes) have been linked to language processing, auditory perception, and speech-related traits, which depend on intact acoustic radiation pathways, while large-scale neuroimaging genetics consortia (e.g., ENIGMA) have reported heritable variation in temporal lobe and auditory white matter that likely encompasses this tract. Clinically, genetic risk factors for developmental language disorder, dyslexia, autism spectrum disorder, and schizophrenia have been associated with altered temporal and thalamocortical connectivity on MRI, indirectly implicating the acoustic radiation, although no major GWAS has yet reported locus-specific effects explicitly tied to the “bilateral WM Acoustic Radiation L” region as defined in the Juelich atlas.
Overview generated by GPT-4o (2026).
Region ID: 94
Hemisphere: bilateral
Atlas: Juelich maxprob thr25 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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