The bilateral Right Cerebrum.Parietal Lobe.Postcentral Gyrus.Gray Matter.Brodmann area 7 corresponds to a subdivision of the superior parietal association cortex involved in higher-order somatosensory processing and visuomotor integration. In the Talairach 1 mm atlas, this region lies posterior to the primary somatosensory cortex and integrates tactile, proprioceptive, and visual information to support spatial perception, body awareness, and coordinated reaching or grasping movements. Neurons in Brodmann area 7 contribute to constructing internal representations of extrapersonal space, transforming sensory input into action-oriented coordinates, and modulating attention to spatial locations. Damage to this area can result in deficits such as impaired spatial orientation, neglect phenomena, or difficulties in visually guided movements. There is no direct link for this exact composite label; a closely related structure is Brodmann area 7.
The bilateral right postcentral gyrus gray matter in parietal Brodmann area 7 (as approximated in the Talairach 1 mm atlas) has been implicated in several genetic and genome-wide association studies, largely via endophenotypes such as cortical thickness, surface area, and regional gray matter volume rather than direct gene–region mapping. Large-scale imaging-genetics consortia (e.g., ENIGMA, UK Biobank) have reported SNP-based heritability and polygenic influences on parietal and postcentral cortical measures, implicating common variants in or near genes involved in neurodevelopment, synaptic function, and axon guidance (for example, loci near genes such as MIR137, BDNF, and WNT pathway components in global parietal morphology), though these are rarely specific to BA7 and often affect broader dorsal parietal and sensorimotor networks. Genetic overlap has been observed between parietal/postcentral morphology and neurodevelopmental and psychiatric conditions, including schizophrenia, ADHD, and autism spectrum disorder, where risk polygenic scores correlate with altered parietal gray matter, as well as with cognitive traits such as general intelligence, visuospatial ability, and educational attainment; in addition, GWAS of chronic pain and somatosensory traits indicate that polygenic risk for these conditions is associated with structural and functional variation in postcentral and superior parietal regions. Overall, the genetic architecture of this BA7/postcentral area appears highly polygenic and shared with wider parietal and sensorimotor networks, with no single gene uniquely or consistently assigned to this precise Talairach-defined region across current GWAS.
Overview generated by GPT-4o (2026).
Region ID: 1102
Hemisphere: bilateral
Atlas: Talairach labels 1mm
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Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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