The bilateral Right Cerebrum.Parietal Lobe.Postcentral Gyrus.White Matter corresponds to the subcortical myelinated fiber pathways underlying the postcentral gyrus within the parietal lobe of the right cerebral hemisphere, encompassing ascending and descending thalamocortical and corticocortical fibers that support somatosensory processing. These white matter tracts convey tactile, proprioceptive, and nociceptive information from the ventral posterior nuclei of the thalamus to the primary somatosensory cortex and interconnect it with other parietal, frontal, and secondary sensory areas, thereby contributing to conscious perception of touch, body position, and integration of sensorimotor signals. Although there is no article specifically for the white matter of the postcentral gyrus, it is structurally and functionally embedded within the Postcentral gyrus.
The bilateral Right Cerebrum.Parietal Lobe.Postcentral Gyrus.White Matter corresponds primarily to the somatosensory projection pathways, and genetic associations involving this region are typically inferred from imaging–genetics and GWAS of brain structure rather than from region-specific single-gene studies. Large-scale neuroimaging GWAS consortia such as ENIGMA and UK Biobank have reported that common variants in genes regulating neurodevelopment, axon guidance, and myelination (for example, variants near or within genes like BDNF, NRG1, CNTNAP2, and myelin-related loci) are associated with cortical thickness, surface area, and white-matter microstructure (e.g., fractional anisotropy) in parietal and postcentral regions. These parietal/postcentral white-matter traits show significant genetic correlations with neurodevelopmental and psychiatric conditions including autism spectrum disorder, attention-deficit/hyperactivity disorder, schizophrenia, and major depressive disorder, as well as with cognitive performance, educational attainment, and sensorimotor functions. Risk loci for multiple sclerosis, leukodystrophies, and other white-matter disorders have also been linked to altered integrity of parietal and postcentral white-matter tracts on MRI, although these associations are usually described at the level of tracts (e.g., superior longitudinal fasciculus, corticospinal and thalamocortical projections) rather than the Talairach-defined postcentral gyrus white matter specifically. Overall, existing genetic evidence implicates polygenic influences on neurodevelopmental patterning, synaptic signaling, and myelination in shaping structural and microstructural variation in this somatosensory white-matter region and its related disease risk, but no single gene or variant is uniquely or consistently tied to the Talairach “Right Cerebrum.Parietal Lobe.Postcentral Gyrus.White Matter” label.
Overview generated by GPT-4o (2026).
Region ID: 786
Hemisphere: bilateral
Atlas: Talairach labels 1mm
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Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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