The bilateral Right Cerebrum.Parietal Lobe.Superior Parietal Lobule.Gray Matter.Brodmann area 7 corresponds to association cortex located in the dorsal superior parietal lobule, extending along the postcentral region posterior to primary somatosensory cortex. Brodmann area 7 integrates multimodal sensory input (somatosensory, visual, and proprioceptive) and is critically involved in spatial perception, visuomotor coordination, body schema representation, and the guidance of eye and limb movements in space. Neuronal populations within this region contribute to higher-order sensorimotor transformations, attention to spatial locations, and the coordination of goal-directed actions, forming part of the dorsal “where/how” visual processing stream and interacting with premotor and posterior parietal regions. There is no direct link for this exact composite label; a related structure is Brodmann area 7.
The bilateral right superior parietal lobule (SPL; Brodmann area 7) has been implicated in several genetic and imaging-genetics studies, though associations are typically reported at the level of parietal or superior parietal gray matter rather than Talairach-specific labels. Twin and family studies show high heritability for SPL thickness, surface area, and volume, with polygenic influences involving pathways for synaptic plasticity, neuronal migration, and axon guidance. Large-scale GWAS of cortical morphology (e.g., ENIGMA, UK Biobank) have identified loci near genes such as HMGA2, MCPH1, and other neurodevelopmental and growth-regulating genes associated with parietal lobe surface area and thickness, and polygenic scores for intelligence and educational attainment correlate with superior parietal structural variation. Functionally, the SPL is central to visuospatial processing, attention, and sensorimotor integration, and genetic studies link parietal structure and connectivity to neurodevelopmental and psychiatric conditions including attention-deficit/hyperactivity disorder, schizophrenia, autism spectrum disorder, and dyslexia, often through risk variants affecting frontoparietal and dorsal attention networks. GWAS of cognitive traits (e.g., working memory, general cognitive ability) and brain functional connectivity have further associated common variants in genes implicated in glutamatergic signaling, synaptic scaffolding, and calcium-channel function with activity and connectivity patterns encompassing right SPL, while rare variant and copy-number studies in neurodevelopmental disorders report parietal structural abnormalities that likely reflect broader genomic perturbations of cortical development rather than SPL-specific genes.
Overview generated by GPT-4o (2026).
Region ID: 1040
Hemisphere: bilateral
Atlas: Talairach labels 1mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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