The bilateral Right Cerebrum.Parietal Lobe.Postcentral Gyrus.White Matter corresponds to the deep myelinated fiber tracts underlying the postcentral gyrus, which houses the primary somatosensory cortex. These white matter pathways include short association fibers connecting adjacent somatosensory areas, longer intra-parietal connections to superior and inferior parietal lobules, and projection fibers that relay tactile, proprioceptive, and nociceptive information to and from subcortical structures such as the thalamus. Functionally, this region supports the integration and rapid transmission of sensory signals essential for conscious perception of body position, texture, and intensity, and for coordination with motor and multimodal association areas involved in sensorimotor integration and spatial representation. There is no direct Wikipedia article for this specific white matter region; a closely related structure is the Postcentral gyrus.
The bilateral Right Cerebrum Parietal Lobe Postcentral Gyrus White Matter corresponds primarily to somatosensory and sensorimotor projection pathways, and most genetic associations arise from studies of cortical structure and white-matter microstructure rather than this Talairach parcel specifically. Large neuroimaging GWAS (e.g., ENIGMA, UK Biobank) have identified multiple loci—commonly near genes such as CADM2, GRIN2A, DLG2, FOXP2, and various axon-guidance and myelination genes (e.g., CNTNAP2, NRG1, MAG, and oligodendrocyte-related loci)—that influence parietal and postcentral cortical thickness, surface area, and diffusion MRI metrics (FA, MD) in adjacent white matter. These structural measures in the postcentral/parietal region show genetic correlations with neurodevelopmental disorders (autism spectrum disorder, ADHD), schizophrenia, and epilepsy, as well as with cognitive traits like general intelligence, processing speed, and educational attainment, implicating genes involved in synaptic plasticity, neurodevelopment, and myelin integrity. Pain-sensitivity and somatosensory GWAS have also highlighted variants in ion-channel and neuroinflammatory genes (e.g., SCN9A, TRPA1, immune-related loci) that modulate activity in somatosensory networks including the postcentral gyrus. While few studies map variants explicitly to the “Right Cerebrum.Parietal Lobe.Postcentral Gyrus.White Matter” Talairach label, convergent genetic evidence points to a polygenic architecture in which common variants affecting cortical and white-matter development, synaptic signaling, and myelination contribute to inter-individual differences in structure and function of this somatosensory projection zone and its involvement in neuropsychiatric and cognitive phenotypes.
Overview generated by GPT-4o (2026).
Region ID: 786
Hemisphere: bilateral
Atlas: Talairach labels 2mm
Full Quality Version: Download MP4
Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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