The bilateral Right Cerebrum.Parietal Lobe.Sub-Gyral.Gray Matter.Brodmann area 7 corresponds to association cortex primarily located in the superior parietal lobule, extending into sub-gyral gray matter beneath the cortical surface. Cytoarchitectonically defined as part of the posterior parietal cortex, Brodmann area 7 integrates visual, somatosensory, and proprioceptive inputs to support spatial perception, visuomotor coordination, and higher-order aspects of attention and body schema. Neuronal populations in this region participate in transforming sensory information into action-relevant representations, contributing to tasks such as reaching, grasping, and navigation in extrapersonal space. Functionally, this area is implicated in multisensory integration, mental imagery of spatial relationships, and aspects of visuospatial working memory within the dorsal visual stream. There is no direct link for this exact Talairach label; a closely related structure is the Superior parietal lobule.
The bilateral Right Cerebrum.Parietal Lobe.Sub-Gyral.Gray Matter.Brodmann area 7 (BA7), a key hub of the superior parietal lobule involved in visuospatial integration, attention, and sensorimotor coordination, has been implicated in multiple genetic and GWAS findings through imaging-genetics and disorder-focused studies. Large-scale brain morphology GWAS (e.g., ENIGMA and UK Biobank–based analyses) have identified common variants near genes such as HMGA2, KIAA0586, and others associated with parietal cortical thickness and surface area, which encompass BA7; polygenic scores for general cognitive ability and educational attainment show positive associations with structural integrity and activation of superior parietal regions. Functionally, BA7 is frequently reported in GWAS-informed fMRI studies of working memory and visuospatial tasks, where genetic variation in dopaminergic and glutamatergic pathways (including COMT, DRD2, and GRM3) modulates activation patterns in parietal cortices. In clinical genetics, BA7 has been linked to neurodevelopmental and psychiatric conditions—autism spectrum disorder, ADHD, schizophrenia, and dyslexia—through convergent evidence that disorder-associated loci (e.g., CACNA1C, CNTNAP2, and FOXP2-related networks) are enriched in circuits involving the superior parietal lobule, often reflected in altered parietal volume or connectivity. Additionally, GWAS of chronic pain, migraine, and body perception disturbances highlight parietal regions including BA7 as downstream neuroanatomical substrates influenced by variants in genes related to synaptic plasticity and neuroinflammation (such as BDNF and CRHR1), suggesting that genetic risk for these traits partly manifests via altered structure and function of the bilateral BA7 region defined in the Talairach 2 mm atlas.
Overview generated by GPT-4o (2026).
Region ID: 1081
Hemisphere: bilateral
Atlas: Talairach labels 2mm
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Full Quality Version: Download MP4
Wali Sidiqyar*, Gaurav Rudravaram*, Elyssa M. McMaster, Trent M. Schwartz, Adam M. Saunders, Kurt G. Schilling, Bennett A. Landman "Introducing SPINS: A Shared Public Visualization Library of Neuroanatomical Structures." Medical Imaging with Deep Learning- short paper
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